Alternatively, for very low glycemia levels, patients would encounter hypoglycemia that could rapidly lead to life-threating events such as coma or death 1. Negligence to preserve certain glycemic targets would probably put the patient at the risk of experiencing the extreme events of hyperglycemia resulting into serious health complications such as heart attack, stroke, kidney failure, blindness, amputation, etc. Typical glucose levels in human beings’ blood for Type-2 diabetes-which is widespread among 90% of the diabetics’ community-normally vary in the range from 72 to 126 mg/dL before having a meal and should be less than 153 mg/dL within 1–2 h after a meal 4. Diabetes is addressed based on the glucose level which cannot be physiologically maintained and standardized for the diabetic patient within the normal desired range, thus indicating the need for the patient to undergo regular medical inspection 2, 3. The presented system is a developmental platform towards radar-driven wearable continuous BGL monitors.ĭiabetes is a metabolic disorder that is caused by the malfunction of steady hormone insulin production by the pancreas, thus degrading the cell’s ability to absorb glucose from the bloodstream 1. Such attractive features promote the proposed sensor as a possible candidate for non-invasive glucose levels monitoring for diabetes as evidenced by the preliminary results from a proof-of-concept in-vivo experiment of tracking an individual’s BGL by placing his fingertip onto the sensor. The proposed sensor, beside its impressive detection capability of the diabetes-spectrum glucose levels, has several other favorable attributes including compact size, simple fabrication, affordable cost, non-ionizing nature, and minimum health risk or impact. Furthermore, the differences in the sensor responses for tested glucose samples are quantified by applying the Principal Component Analysis (PCA) machine learning algorithm. This is also demonstrated in the radar-driven prototype where the raw data collected at the radar receiving channel shows obvious patterns that reflect glucose-level variations. The desired performance of the fabricated sensor is practically validated through in-vitro measurements using a convenient setup of Vector Network Analyzer (VNA) that records notable traces of frequency-shift responses when the sensor is loaded with samples of 70–120 mg/dL glucose concentrations. This feature enables the developed sensor to detect extremely delicate variations in the electromagnetic properties that characterize the varying-level glucose samples. The superior detection capability is attributed to the enhanced design of the CSRR sensing elements that expose the glucose samples to an intense interaction with the electromagnetic fields highly concentrated around the sensing region at the induced resonances. The integrated sensor shows an impressive detection capability and a remarkable sensitivity of blood glucose levels (BGLs). The proposed sensor design incorporates four cells of hexagonal-shaped complementary split ring resonators (CSRRs), arranged in a honey-cell configuration, and fabricated on a thin sheet of an FR4 dielectric substrate.The CSRR sensing elements are coupled via a planar microstrip-line to a radar board operating in the ISM band 2.4–2.5 GHz. This article presents a novel design of portable planar microwave sensor for fast, accurate, and non-invasive monitoring of the blood glucose level as an effective technique for diabetes control and prevention.
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